Show: House

House encounters a brain-damaged musical prodigy with inexplicable abilities while the team faces serious concerns about House’s own health.

The team takes on the case of an ailing groom-to-be who harbors undisclosed secrets from a previous relationship. As his fiancée tries to get answers to her many questions, a frustrated team winnows down the possibilities. Meanwhile, House spends extra-curricular time with his Princeton Plainsboro colleagues, performing a karaoke rendition of a Gladys Knight & The Pips classic with Foreman and Chase.

A gun-wielding man from the waiting room at the Princeton-Plainsboro clinic takes House, Thirteen and several patients from the waiting room hostage in Cuddy’s office. The man claims to be sick with a long undiagnosed illness and demands medical attention from the best doctor in the hospital, threatening to kill any hostages necessary along the way.

After a 200-year-old medicine jar found on an off-shore shipwreck shatters in a teenage girl’s palm, she is admitted to Princeton Plainsboro for symptoms closely linked to smallpox.

Melinda, a troubled teenage girl who is immuno-compromised as a result of the medications she must take after a heart transplant, has a severe allergic reaction and goes into shock when her boyfriend visits her. Meanwhile, House and Wilson continue to work out the problems in their new living arrangement.

While attending his editor’s retirement party, a journalist collapses and hits his head on a desk. When he regains consciousness, his sentences are garbled and incoherent, so he is rushed to Princeton Plainsboro Teaching Hospital. With House and Stacy stranded at an airport due to bad weather, the team is forced to solve the case with House helping out over the phone.

Andie, a 9-year-old terminal cancer patient, is brought in after suffering from a hallucinogenic episode. Wilson convinces House to take the case, but he and his team struggle to diagnose what caused the hallucination. Andie handles the reality of her terminal medical situation remarkably well – so well that House questions the sincerity of her bravery and considers the possibility it may be a medical symptom.

Meanwhile, Andie’s request to experience one of life’s great “firsts” forces Dr. Chase to make a difficult personal decision. House has an idea of what’s causing Andie’s medical emergency, but puts the decision in her hands as to whether to take on an extremely risky experimental treatment, one that may end her life even sooner than her terminal illness.

A 6-year-old girl suffers ailments expected in patients much older. Tensions between Chase and Cameron lead House to intentionally assign them to the same tasks, including investigating the young girl’s home.

The team takes on the case of a lottery winner (Donal Logue) suffering from paralysis and multiple types of cancer, and they must figure out if it his new millionaire lifestyle that is making him sick. Meanwhile, Cuddy’s mother threatens to sue the hospital over her treatment, and Foreman and Chase make a bet over who is repressing the uglier side of their personality more.

The team takes on the case of Valerie, an attractive female executive experiencing random episodes of excruciating pain. House agrees to take the case based on Valerie’s looks, and while treating her, the men on the team are charmed by Valerie’s beauty and personality, with Thirteen looking beyond the superficial to try to discover a link to her illness. Meanwhile, House uncharacteristically attempts to alleviate his conscience by reaching out to a former medical school colleague he wronged.

Over the years, during the course of performing autopsies at Princeton-Plainsboro, Dr. Peter Treiber has often identified mistakes made by physicians that caused the patient’s death. These observations have left him questioning the skills of nearly all the doctors on staff… all, that is, except House. When he falls ill, he demands that only House make medical decisions concerning his care. Unfortunately, House and Wilson have taken off on an impromptu road trip without telling anyone, leaving the team to fend alone and lie to their patient to make him believe that House is the guy calling all the shots.

House takes the case of a man who experienced a seizure but wasn’t aware it happened. When the man suffers a heart attack and needs a heart transplant, the team races to diagnose a dead woman’s illness so they can harvest her heart to save their living patient.

House asks Alvie to help him uncover incriminating information about Dr. Nolan that would allow him to blackmail his way out of the treatment center and convinces Lydia to loan him her car to sneak out a delusional patient in an attempt by House to undermine Dr. Nolan’s course of treatment. But when devastating events ensue, House is humbled into reluctantly accepting help.

Thirteen has been in prison for the past year, but the real mystery for House is what she did to get there. At the hospital, the team treats a science teacher suffering from severe respiratory illness. Taub tries to get back into the dating scene, but winds up retreating to his old habits.

House’s green-card wife, Dominika, will return in order to prove to the proper authorities that she and House are actually married. This in turn will lead to a crash course in which both will learn a little something about love and marriage.

Legendary jazz musician John Henry Giles is checked into the hospital and when he’s told he’s dying from ALS, he signs a DNR to avoid a slow death. House disagrees with the diagnosis and goes against everyone’s wishes when he violates the DNR to save Giles’ life. The decision lands House in court, drives Foreman to consider taking another job, and results in Giles’ paralysis worsening. But when the patient inexplicably starts getting better, the team has to figure out the mystery in reverse and find out why his condition is improving.

House and the team take on the case of a ballerina whose lungs collapse in the middle of a performance. When the treatment causes her skin to fall off, the dancer faces not only the prospect of never dancing again but also of dying an agonizing death. The team must use their imaginations to carefully choreograph ways to test and treat her delicate body without killing her. Meanwhile, House continues to suffer from what he thinks is insomnia, and he is willing to go to desperate measures to cure it.

House and his team have to diagnose a case at a distance when a researcher at a South Pole base is taken ill.

“Lockdown” is the sixteenth episode of the sixth season of the American medical drama House. It aired on April 12, 2010. This episode also marks the directorial debut of Hugh Laurie on the show.

This episode has five storylines: When the hospital is sent into lock-down mode due to a missing infant, all of the doctors must remain where they are, leaving Foreman and Taub in the file room, Wilson and Thirteen in the cafeteria playing truth or dare, House in a room with a patient, and Chase with his soon-to-be ex-wife, Cameron, as Cuddy tries to help police locate the infant. This episode is one of the show’s rare instances when no medical mystery is presented, though House still deals with his “patient of the week”.

House uncovers a startling secret when he treats a teenage supermodel for heroin addiction. Meanwhile, Wilson hopes the increased leg pain in House’s leg is an indication his leg nerves are regenerating.